Research ArticleNEONATAL JAUNDICE

Bilirubin enhances the activity of ASIC channels to exacerbate neurotoxicity in neonatal hyperbilirubinemia in mice

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Science Translational Medicine  12 Feb 2020:
Vol. 12, Issue 530, eaax1337
DOI: 10.1126/scitranslmed.aax1337

Article Information

vol. 12 no. 530

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History: 
  • Received for publication February 25, 2019
  • Resubmitted August 3, 2019
  • Accepted for publication December 10, 2019
  • .

Author Information

  1. Ke Lai1,*,
  2. Xing-Lei Song2,*,
  3. Hao-Song Shi1,*,
  4. Xin Qi2,
  5. Chun-Yan Li1,
  6. Jia Fang1,
  7. Fan Wang1,
  8. Oleksandr Maximyuk3,
  9. Oleg Krishtal3,
  10. Tian-Le Xu2,
  11. Xiao-Yan Li4,
  12. Kun Ni4,
  13. Wan-Peng Li4,
  14. Hai-Bo Shi1,,
  15. Lu-Yang Wang5,6, and
  16. Shan-Kai Yin1,
  1. 1Department of Otorhinolaryngology, Sixth People’s Hospital of Shanghai and Shanghai Jiao Tong University, Shanghai 200032, China.
  2. 2Department of Anatomy and Physiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
  3. 3Bogomoletz Institute of Physiology of NAS Ukraine, Kyiv 01024, Ukraine.
  4. 4Department of Otorhinolaryngology, Shanghai Children Hospital and Shanghai Jiao Tong University, Shanghai 200062, China.
  5. 5Program in Neuroscience and Mental Health, SickKids Research Institute, Toronto M5G 1X8, Canada.
  6. 6Department of Physiology, University of Toronto, Toronto M5S 1A1, Canada.
  1. Corresponding author. Email: hbshi{at}sjtu.edu.cn (H.-B.S.); luyang.wang{at}utoronto.ca (L.-Y.W.); skyin{at}sjtu.edu.cn (S.-K.Y.)
  • * These authors contributed equally to this work.

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