Research ArticleCancer
Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies
- View ORCID ProfileCandice R. Gurbatri1,
- Ioana Lia1,
- View ORCID ProfileRosa Vincent1,
- Courtney Coker1,
- View ORCID ProfileSamuel Castro1,
- View ORCID ProfilePiper M. Treuting2,
- Taylor E. Hinchliffe1,
- View ORCID ProfileNicholas Arpaia3,4 and
- View ORCID ProfileTal Danino1,4,5,*
- 1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.
- 2Department of Comparative Medicine, University of Washington, Seattle, WA 98195, USA.
- 3Department of Microbiology & Immunology, Vagelos College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.
- 4Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10027, USA.
- 5Data Science Institute, Columbia University, New York, NY 10027, USA.
- ↵*Corresponding author. Email: td2506{at}columbia.edu
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Science Translational Medicine 12 Feb 2020:
Vol. 12, Issue 530, eaax0876
DOI: 10.1126/scitranslmed.aax0876
Vol. 12, Issue 530, eaax0876
DOI: 10.1126/scitranslmed.aax0876
Candice R. Gurbatri
1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.
Ioana Lia
1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.
Rosa Vincent
1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.
Courtney Coker
1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.
Samuel Castro
1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.
Piper M. Treuting
2Department of Comparative Medicine, University of Washington, Seattle, WA 98195, USA.
Taylor E. Hinchliffe
1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.
Nicholas Arpaia
3Department of Microbiology & Immunology, Vagelos College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.
4Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10027, USA.
Tal Danino
1Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA.
4Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10027, USA.
5Data Science Institute, Columbia University, New York, NY 10027, USA.
