Research ArticleNEURODEGENERATIVE DISEASES

APOE genotype regulates pathology and disease progression in synucleinopathy

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Science Translational Medicine  05 Feb 2020:
Vol. 12, Issue 529, eaay3069
DOI: 10.1126/scitranslmed.aay3069

Article Information

vol. 12 no. 529

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History: 
  • Received for publication June 6, 2019
  • Accepted for publication December 3, 2019
  • .

Author Information

  1. Albert A. Davis1,2,*,
  2. Casey E. Inman1,2,
  3. Zachary M. Wargel1,2,
  4. Umber Dube1,3,
  5. Brittany M. Freeberg1,2,
  6. Alexander Galluppi1,2,
  7. Jessica N. Haines1,2,
  8. Dhruva D. Dhavale1,2,
  9. Rebecca Miller1,2,
  10. Fahim A. Choudhury1,2,
  11. Patrick M. Sullivan4,
  12. Carlos Cruchaga1,3,
  13. Joel S. Perlmutter1,2,5,
  14. Jason D. Ulrich1,2,
  15. Bruno A. Benitez1,3,
  16. Paul T. Kotzbauer1,2 and
  17. David M. Holtzman1,2,6,*
  1. 1Hope Center for Neurologic Disease, Washington University, St. Louis, MO 63110, USA.
  2. 2Department of Neurology, Washington University, St. Louis, MO 63110, USA.
  3. 3Department of Psychiatry, Washington University, St. Louis, MO 63110, USA.
  4. 4Department of Medicine, Duke University Medical Center, Durham VAMC and Geriatric Research Clinical Center, Durham, NC 27705, USA.
  5. 5Departments of Neuroscience and Radiology, Programs in Physical and Occupational Therapy, Washington University, St. Louis, MO 63110, USA.
  6. 6Knight Alzheimer’s Disease Research Center, Washington University, St. Louis, MO 63110, USA.
  1. *Corresponding author. Email: albert.a.davis{at}wustl.edu (A.A.D.); holtzman{at}wustl.edu (D.M.H.)

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