Research ArticleHYPERTRIGLYCERIDEMIA

A dual apolipoprotein C-II mimetic–apolipoprotein C-III antagonist peptide lowers plasma triglycerides

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Science Translational Medicine  29 Jan 2020:
Vol. 12, Issue 528, eaaw7905
DOI: 10.1126/scitranslmed.aaw7905

Article Information

vol. 12 no. 528

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication January 25, 2019
  • Accepted for publication December 6, 2019
  • .

Author Information

  1. Anna Wolska1,*,
  2. Larry Lo2,
  3. Denis O. Sviridov1,
  4. Mohsen Pourmousa3,
  5. Milton Pryor1,
  6. Soumitra S. Ghosh2,
  7. Rahul Kakkar2,
  8. Michael Davidson2,
  9. Sierra Wilson1,
  10. Richard W. Pastor3,
  11. Ira J. Goldberg4,
  12. Debapriya Basu4,
  13. Steven K. Drake5,
  14. Antony Cougnoux6,
  15. Ming Jing Wu7,
  16. Saskia B. Neher7,
  17. Lita A. Freeman1,
  18. Jingrong Tang1,
  19. Marcelo Amar1,
  20. Matt Devalaraja2,*, and
  21. Alan T. Remaley1,*,
  1. 1Lipoprotein Metabolism Laboratory, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  2. 2Corvidia Therapeutics Inc., Waltham, MA 02451, USA.
  3. 3Laboratory of Computational Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  4. 4Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA.
  5. 5Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA.
  6. 6Division of Translational Medicine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
  7. 7Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27599, USA.
  1. *Corresponding author. Email: aremaley1{at}nhlbi.nih.gov (A.T.R.); anna.wolska{at}nih.gov (A.W.); matt{at}corvidiatx.com (M. Devalaraja)
  • These authors share senior authorship.

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