Pan-viral protection against arboviruses by activating skin macrophages at the inoculation site

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Science Translational Medicine  22 Jan 2020:
Vol. 12, Issue 527, eaax2421
DOI: 10.1126/scitranslmed.aax2421

Article Information

vol. 12 no. 527

Print ISSN: 
Online ISSN: 
  • Received for publication March 6, 2019
  • Resubmitted August 16, 2019
  • Accepted for publication December 30, 2019
  • .

Author Information

  1. Steven R. Bryden1,2,
  2. Marieke Pingen1,2,
  3. Daniella A. Lefteri1,
  4. Janne Miltenburg1,
  5. Leen Delang3,
  6. Sofie Jacobs3,
  7. Rana Abdelnabi3,
  8. Johan Neyts3,
  9. Emilie Pondeville4,
  10. Jack Major1,2,
  11. Marietta Müller5,
  12. Henna Khalid5,
  13. Andrew Tuplin5,
  14. Margus Varjak2,
  15. Andres Merits6,
  16. Julia Edgar2,
  17. Gerard J. Graham2,
  18. Kave Shams7 and
  19. Clive S. McKimmie1,*
  1. 1Virus Host Interaction Team, Leeds Institute of Medical Research, School of Medicine, Faculty of Medicine and Health, University of Leeds, Leeds LS9 7TF, UK.
  2. 2Institute of Infection, Immunology and Inflammation, University of Glasgow, Glasgow G12 8TA, UK.
  3. 3KU Leuven Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, 3000 Leuven, Belgium.
  4. 4MRC‑University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK.
  5. 5School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
  6. 6Institute of Technology, University of Tartu, 50411 Tartu, Estonia.
  7. 7Inflammatory Skin Disease Group, Institute of Rheumatic and Musculoskeletal Medicine, School of Medicine, Faculty of Medicine and Health, University of Leeds, Leeds LS9 7TF, UK.
  1. *Corresponding author. Email: c.s.mckimmie{at}


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