Research ArticleStem Cell Transplantation

Engraftment of rare, pathogenic donor hematopoietic mutations in unrelated hematopoietic stem cell transplantation

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Science Translational Medicine  15 Jan 2020:
Vol. 12, Issue 526, eaax6249
DOI: 10.1126/scitranslmed.aax6249

Article Information

vol. 12 no. 526

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication April 9, 2019
  • Resubmitted June 20, 2019
  • Accepted for publication November 27, 2019
  • .

Author Information

  1. Wing Hing Wong1,2,
  2. Sima Bhatt1,
  3. Kathryn Trinkaus3,
  4. Iskra Pusic4,
  5. Kevin Elliott4,
  6. Nitin Mahajan1,2,
  7. Fei Wan3,
  8. Galen E. Switzer5,
  9. Dennis L. Confer6,
  10. John DiPersio4,
  11. Michael A. Pulsipher7,
  12. Nirali N. Shah8,
  13. Jennifer Sees6,
  14. Amelia Bystry1,2,
  15. Jamie R. Blundell9,
  16. Bronwen E. Shaw10 and
  17. Todd E. Druley1,2,*
  1. 1Division of Hematology and Oncology, Department of Pediatrics, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.
  2. 2The Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, 4515 McKinley Avenue, St. Louis, MO 63110, USA.
  3. 3Division of Public Health Sciences, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.
  4. 4Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.
  5. 5Department of Medicine, University of Pittsburgh, 3550 Terrace St., Pittsburgh, PA 15261, USA.
  6. 6Center for International Blood and Marrow Transplant Research, National Marrow Donor Problem/Be The Match, 500 North 5th St, Minneapolis, MN 55401, USA.
  7. 7Children's Center for Cancer and Blood Diseases, Children’s Hospital Los Angeles, Keck School of Medicine, University of Southern California, 4650 Sunset Blvd., Los Angeles, CA 90027, USA.
  8. 8Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA.
  9. 9CRUK Cambridge Centre Early Detection Program, Department of Oncology, Hutchison/MRC Research Center, University of Cambridge, Hills Road, Cambridge CB2 0XZ, UK.
  10. 10Center for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, 9200 West Wisconsin Ave., Milwaukee, WI 53226, USA.
  1. *Corresponding author. Email: druley_t{at}wustl.edu

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