Research ArticlePANCREATITIS

Pancreatitis is an FGF21-deficient state that is corrected by replacement therapy

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Science Translational Medicine  08 Jan 2020:
Vol. 12, Issue 525, eaay5186
DOI: 10.1126/scitranslmed.aay5186

Article Information

vol. 12 no. 525

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  • Received for publication June 25, 2019
  • Accepted for publication December 9, 2019
  • .

Author Information

  1. Genaro Hernandez1,
  2. Ting Luo1,
  3. Tanveer A. Javed2,
  4. Li Wen3,
  5. Michael A. Kalwat1,
  6. Kevin Vale1,
  7. Farah Ammouri1,
  8. Sohail Z. Husain4,
  9. Steven A. Kliewer1,5,* and
  10. David J. Mangelsdorf1,6,*
  1. 1Department of Pharmacology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  2. 2Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA 15224, USA.
  3. 3Department of Gastroenterology and Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.
  4. 4Department of Pediatrics, Stanford University, Palo Alto, CA 94305, USA.
  5. 5Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  6. 6Howard Hughes Medical Institute, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  1. *Corresponding author. Email: steven.kliewer{at} (S.A.K.);{at} (D.J.M.)


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