Research ArticleObesity
Physiological consequences of transient hyperleptinemia during discrete developmental periods on body weight in mice
- View ORCID ProfileAlicja A. Skowronski1,
- View ORCID ProfileCharles A. LeDuc1,2,
- View ORCID ProfileKylie S. Foo1,*,
- View ORCID ProfileYossef Goffer1,
- View ORCID ProfileLisa C. Burnett1,†,
- Dieter Egli1,2,3 and
- View ORCID ProfileRudolph L. Leibel1,2,‡
- 1Division of Molecular Genetics, Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY 10032, USA.
- 2Naomi Berrie Diabetes Center, Columbia University Irving Medical Center, New York, NY 10032, USA.
- 3Department of Obstetrics and Gynecology, and Columbia Stem Cell Initiative, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY 10032, USA.
- ↵‡Corresponding author. Email: rl232{at}cumc.columbia.edu
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Science Translational Medicine 01 Jan 2020:
Vol. 12, Issue 524, eaax6629
DOI: 10.1126/scitranslmed.aax6629
Vol. 12, Issue 524, eaax6629
DOI: 10.1126/scitranslmed.aax6629
Alicja A. Skowronski
1Division of Molecular Genetics, Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY 10032, USA.
Charles A. LeDuc
1Division of Molecular Genetics, Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY 10032, USA.
2Naomi Berrie Diabetes Center, Columbia University Irving Medical Center, New York, NY 10032, USA.
Kylie S. Foo
1Division of Molecular Genetics, Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY 10032, USA.
Yossef Goffer
1Division of Molecular Genetics, Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY 10032, USA.
Lisa C. Burnett
1Division of Molecular Genetics, Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY 10032, USA.
Dieter Egli
1Division of Molecular Genetics, Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY 10032, USA.
2Naomi Berrie Diabetes Center, Columbia University Irving Medical Center, New York, NY 10032, USA.
3Department of Obstetrics and Gynecology, and Columbia Stem Cell Initiative, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY 10032, USA.
Rudolph L. Leibel
1Division of Molecular Genetics, Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY 10032, USA.
2Naomi Berrie Diabetes Center, Columbia University Irving Medical Center, New York, NY 10032, USA.