Research ArticleHIV

Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells

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Science Translational Medicine  18 Dec 2019:
Vol. 11, Issue 523, eaax4077
DOI: 10.1126/scitranslmed.aax4077

Article Information

vol. 11 no. 523

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication March 29, 2019
  • Resubmitted September 3, 2019
  • Accepted for publication November 11, 2019
  • .

Author Information

  1. Son Nguyen1,
  2. Claire Deleage2,
  3. Samuel Darko3,
  4. Amy Ransier3,
  5. Duc P. Truong4,
  6. Divyansh Agarwal5,
  7. Alberto Sada Japp1,
  8. Vincent H. Wu1,
  9. Leticia Kuri-Cervantes1,
  10. Mohamed Abdel-Mohsen6,
  11. Perla M. Del Rio Estrada7,
  12. Yuria Ablanedo-Terrazas7,
  13. Emma Gostick8,
  14. James A. Hoxie9,
  15. Nancy R. Zhang5,
  16. Ali Naji10,
  17. Gustavo Reyes-Terán7,
  18. Jacob D. Estes11,12,
  19. David A. Price8,
  20. Daniel C. Douek3,
  21. Steven G. Deeks13,
  22. Marcus Buggert14,* and
  23. Michael R. Betts1,*,
  1. 1Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  2. 2AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD 21702, USA.
  3. 3Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  4. 4Department of Mathematics, Southern Methodist University, Dallas, TX 75205, USA.
  5. 5Department of Statistics, University of Pennsylvania, Philadelphia, PA 19104, USA.
  6. 6The Wistar Institute, Philadelphia, PA 19104, USA.
  7. 7Departamento de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias, Mexico City 14080, Mexico.
  8. 8Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.
  9. 9Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  10. 10Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  11. 11Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, OR 97239, USA.
  12. 12Division of Pathobiology and Immunology, Oregon National Primate Research Center, Oregon Health and Science University, Portland, OR 97239, USA.
  13. 13Department of Medicine, University of California, San Francisco General Hospital, San Francisco, CA 94110, USA.
  14. 14Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital Huddinge, 14186 Stockholm, Sweden.
  1. Corresponding author. Email: betts{at}pennmedicine.upenn.edu
  • * These authors contributed equally to this work.

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