Research ArticleHIV

Early antiretroviral therapy in neonates with HIV-1 infection restricts viral reservoir size and induces a distinct innate immune profile

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Science Translational Medicine  27 Nov 2019:
Vol. 11, Issue 520, eaax7350
DOI: 10.1126/scitranslmed.aax7350

Article Information

vol. 11 no. 520

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History: 
  • Received for publication April 19, 2019
  • Accepted for publication October 11, 2019
  • .

Author Information

  1. Pilar Garcia-Broncano1,
  2. Shivaali Maddali1,
  3. Kevin B. Einkauf1,2,
  4. Chenyang Jiang1,2,
  5. Ce Gao1,
  6. Joshua Chevalier1,2,
  7. Fatema Z. Chowdhury1,
  8. Kenneth Maswabi3,
  9. Gbolahan Ajibola3,
  10. Sikhulile Moyo3,
  11. Terence Mohammed3,
  12. Thabani Ncube3,
  13. Joseph Makhema3,
  14. Patrick Jean-Philippe4,
  15. Xu G. Yu1,2,5,
  16. Kathleen M. Powis3,5,6,7,
  17. Shahin Lockman2,3,5,
  18. Daniel R. Kuritzkes2,5,
  19. Roger Shapiro3,5,7 and
  20. Mathias Lichterfeld1,2,5,*
  1. 1Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.
  2. 2Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA 02115, USA.
  3. 3Botswana-Harvard AIDS Institute Partnership, Gaborone, Botswana.
  4. 4Division of AIDS, NIAID, NIH, Rockville, MD 20852, USA.
  5. 5Harvard Medical School, Boston, MA 02115, USA.
  6. 6Departments of Medicine and Pediatrics, Massachusetts General Hospital, Boston, MA 02114, USA.
  7. 7Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
  1. *Corresponding author. Email: mlichterfeld{at}partners.org

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