Research ArticleHIV

Antigenic competition in CD4+ T cell responses in a randomized, multicenter, double-blind clinical HIV vaccine trial

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Science Translational Medicine  20 Nov 2019:
Vol. 11, Issue 519, eaaw1673
DOI: 10.1126/scitranslmed.aaw1673

Article Information

vol. 11 no. 519

PubMed: 
Print ISSN: 
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History: 
  • Received for publication November 24, 2018
  • Accepted for publication October 4, 2019
  • .

Author Information

  1. Esper G. Kallas1,
  2. Nicole A. Grunenberg2,
  3. Chenchen Yu2,
  4. Bryce Manso2,
  5. Giuseppe Pantaleo3,
  6. Martin Casapia4,
  7. Lindsey R. Baden5,
  8. Javier Valencia6,
  9. Magdalena Sobieszczyk7,
  10. Hong Van Tieu8,
  11. Mary Allen9,
  12. John Hural2,
  13. Barney S. Graham10,
  14. James Kublin2,
  15. Peter B. Gilbert2,
  16. Lawrence Corey2,
  17. Paul A. Goepfert11,
  18. M. Juliana McElrath2,12,13,14,
  19. R. Paul Johnson15,
  20. Yunda Huang2 and
  21. Nicole Frahm2,12,*
  1. 1Division of Clinical Immunology and Allergy, University of São Paulo, São Paulo 05508, Brazil.
  2. 2Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  3. 3Division of Immunology and Allergy, Lausanne University Hospital (CHUV), 1011 Lausanne, Switzerland.
  4. 4Asociación Civil Selva Amazónica, Iquitos 16002, Peru.
  5. 5Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
  6. 6Asociación Civil Impacta Salud Y Educación, Lima 15063, Peru.
  7. 7Division of Infectious Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA.
  8. 8Laboratory of Infectious Disease Prevention, New York Blood Center, New York, NY 10065, USA.
  9. 9Division of AIDS, National Institute for Allergy and Infectious Diseases, NIH, Bethesda, MD 20892, USA.
  10. 10Vaccine Research Center, NIH, Bethesda, MD 20892, USA.
  11. 11Division of Infectious Disease and Department of Surgery, Division of Gastroenterology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  12. 12Department of Global Health, University of Washington, Seattle, WA 98195, USA.
  13. 13Department of Laboratory Medicine, University of Washington, Seattle, WA 98195, USA.
  14. 14Department of Medicine, University of Washington, Seattle, WA 98195, USA.
  15. 15Yerkes National Primate Research Center, School of Medicine, Emory University, Atlanta, GA 30322, USA.
  1. *Corresponding author. Email: nicole.frahm{at}gatesmri.org

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