Editors' ChoiceCancer

A new hope? Yoda1 uses the “force” to sensitize cancer cells to TRAIL-mediated apoptosis

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Science Translational Medicine  13 Nov 2019:
Vol. 11, Issue 518, eaaz9752
DOI: 10.1126/scitranslmed.aaz9752

Abstract

A mechanosensitive ion channel agonist mimics shear stress to enhance the cytotoxic effects of TRAIL on cancer cells.

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