Research ArticleDrug Delivery

A heat-stable microparticle platform for oral micronutrient delivery

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Science Translational Medicine  13 Nov 2019:
Vol. 11, Issue 518, eaaw3680
DOI: 10.1126/scitranslmed.aaw3680

Article Information

vol. 11 no. 518

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication December 13, 2018
  • Accepted for publication September 16, 2019
  • .

Author Information

  1. Aaron C. Anselmo1,*,,
  2. Xian Xu1,*,
  3. Simone Buerkli2,*,
  4. Yingying Zeng1,
  5. Wen Tang1,
  6. Kevin J. McHugh1,,
  7. Adam M. Behrens1,
  8. Evan Rosenberg1,
  9. Aranda R. Duan1,
  10. James L. Sugarman1,
  11. Jia Zhuang1,
  12. Joe Collins1,
  13. Xueguang Lu1,
  14. Tyler Graf1,
  15. Stephany Y. Tzeng1,
  16. Sviatlana Rose1,
  17. Sarah Acolatse1,
  18. Thanh D. Nguyen1,§,
  19. Xiao Le1,
  20. Ana Sofia Guerra3,
  21. Lisa E. Freed1,||,
  22. Shelley B. Weinstock4,
  23. Christopher B. Sears5,
  24. Boris Nikolic6,
  25. Lowell Wood7,
  26. Philip A. Welkhoff7,,
  27. James D. Oxley8,
  28. Diego Moretti2,#,
  29. Michael B. Zimmermann2,
  30. Robert Langer1,** and
  31. Ana Jaklenec1,**
  1. 1David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  2. 2Institute of Food Nutrition and Health, ETH Zürich, Zürich 8092, Switzerland.
  3. 3Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
  4. 4Institute of Human Nutrition, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
  5. 5Independent Scholar, Belmont, MA 02478, USA.
  6. 6Biomatics Capital, 1107 1st Avenue, Apartment 1305, Seattle, WA 98101, USA.
  7. 7Institute for Disease Modeling, Bellevue, WA 98005, USA.
  8. 8Southwest Research Institute, San Antonio, TX 78238, USA.
  1. **Corresponding author. Email: jaklenec{at}mit.edu (A.J.); rlanger{at}mit.edu (R.L.)
  • * These authors contributed equally to this work.

  • Present address: Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

  • Present address: Department of Bioengineering, Rice University, Houston, TX 77030, USA.

  • § Present address: Department of Mechanical Engineering, University of Connecticut, Storrs, CT 06269, USA.

  • || Present address: Media Lab, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

  • Present address: The Bill & Melinda Gates Foundation, Seattle, WA 98109, USA.

  • # Present address: Nutrition Group, Health Department, Swiss Distance University of Applied Sciences, Regensdorf CH-8105, Switzerland.

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