Research ArticleMultiple Sclerosis

Activated leukocyte cell adhesion molecule regulates B lymphocyte migration across central nervous system barriers

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Science Translational Medicine  13 Nov 2019:
Vol. 11, Issue 518, eaaw0475
DOI: 10.1126/scitranslmed.aaw0475

Article Information

vol. 11 no. 518

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History: 
  • Received for publication November 26, 2018
  • Resubmitted July 10, 2019
  • Accepted for publication October 21, 2019
  • .

Author Information

  1. Laure Michel1,2,*,,,
  2. Camille Grasmuck1,2,*,
  3. Marc Charabati1,2,
  4. Marc-André Lécuyer1,2,
  5. Stephanie Zandee1,2,
  6. Tessa Dhaeze1,2,
  7. Jorge I. Alvarez1,2,§,
  8. Rui Li3,
  9. Sandra Larouche1,2,
  10. Lyne Bourbonnière1,2,
  11. Robert Moumdjian4,
  12. Alain Bouthillier4,
  13. Boaz Lahav1,2,
  14. Pierre Duquette1,2,
  15. Amit Bar-Or3,
  16. Jennifer L. Gommerman5,
  17. Evelyn Peelen1,2 and
  18. Alexandre Prat1,2,||
  1. 1Department of Neuroscience, Faculty of Medicine, Université de Montréal, Montréal, QC Canada.
  2. 2Neuroimmunology Unit, Centre de recherche du CHUM (CRCHUM), Montréal, QC H2X 0A9, Canada.
  3. 3Center for Neuroinflammation and Experimental Therapeutics and Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  4. 4Division of Neurosurgery, CHUM, Montréal, QC H2X 3E4, Canada.
  5. 5Department of Immunology, University of Toronto, Toronto, ON M5S 1A8, Canada.
  1. ||Corresponding author. Email: a.prat{at}umontreal.ca
  • * These authors contributed equally to this work.

  • Present address: Department of Neurology, CIC P14-14 INSERM, CHU Pontchaillou, 35033 Rennes Cedex, France.

  • Present address: Université de Rennes, Établissement Français du Sang (EFS) de Bretagne, Inserm, MICMAC-UMR_S1236, Rennes, France.

  • § Present address: Department of Pathobiology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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