Editors' ChoiceNEURODEVELOPMENTAL DISORDERS

A no-nonsense treatment for autism spectrum disorder

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Science Translational Medicine  30 Oct 2019:
Vol. 11, Issue 516, eaaz3723
DOI: 10.1126/scitranslmed.aaz3723

Abstract

Mutation of the nonsense-mediated mRNA decay factor Upf2 leads to neurological phenotypes that can be corrected with immunosuppressive drugs in mice.

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