Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response

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  Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response

  By David Sharon, Severine Cathelin, Sara Mirali, Justin M. Di Trani, David J. Yanofsky, Kristine A. Keon, John L. Rubinstein, Aaron D. Schimmer, Troy Ketela, Steven M. Chan

  Science Translational Medicine30 Oct 2019

  Tedizolid, an oxazolidinone-class antibiotic, overcomes resistance to venetoclax in AML.

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  Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response

  By David Sharon, Severine Cathelin, Sara Mirali, Justin M. Di Trani, David J. Yanofsky, Kristine A. Keon, John L. Rubinstein, Aaron D. Schimmer, Troy Ketela, Steven M. Chan

  Science Translational Medicine30 Oct 2019

  Tedizolid, an oxazolidinone-class antibiotic, overcomes resistance to venetoclax in AML.

  • Supplementary Materials

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