FocusImmunotherapy

Intratumoral CD8+ T cells with stem cell–like properties: Implications for cancer immunotherapy

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Science Translational Medicine  23 Oct 2019:
Vol. 11, Issue 515, eaay6863
DOI: 10.1126/scitranslmed.aay6863

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Abstract

Intratumoral PD-1+ TCF1+ CD8+ T cells with stem cell–like properties mediate cellular expansion and tumor control in response to immunotherapy.

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