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Repurposing rotavirus vaccines for intratumoral immunotherapy can overcome resistance to immune checkpoint blockade

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Science Translational Medicine  23 Oct 2019:
Vol. 11, Issue 515, eaat5025
DOI: 10.1126/scitranslmed.aat5025

Article Information

vol. 11 no. 515

PubMed: 
Print ISSN: 
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History: 
  • Received for publication March 14, 2018
  • Resubmitted April 18, 2019
  • Accepted for publication September 25, 2019
  • .

Author Information

  1. Tala Shekarian1,2,3,4,
  2. Eva Sivado2,3,5,
  3. Anne-Catherine Jallas2,5,
  4. Stéphane Depil1,2,3,
  5. Janice Kielbassa6,
  6. Isabelle Janoueix-Lerosey7,8,
  7. Gregor Hutter4,
  8. Nadège Goutagny1,2,
  9. Christophe Bergeron2,9,
  10. Alain Viari6,10,
  11. Sandrine Valsesia-Wittmann2,5,*,
  12. Christophe Caux1,2,* and
  13. Aurélien Marabelle2,9,11,12,*,
  1. 1Centre de Recherche en Cancérologie de Lyon (CRCL), UMR INSERM U1052 CNRS 5286 Université de Lyon, 69008 Lyon, France.
  2. 2Centre de Lutte contre le Cancer Léon Bérard, 69008 Lyon, France.
  3. 3Université Claude Bernard Lyon 1, 69100 Villeurbanne France.
  4. 4University Hospital Basel, 4031 Basel, Switzerland.
  5. 5INSERM UA8, 69008 Lyon, France.
  6. 6Synergie Lyon Cancer, Plateforme de bioinformatique ‘Gilles Thomas’, Centre Léon Bérard, 69008 Lyon, France.
  7. 7Institut Curie, PSL Research University, Inserm U830, 75005 Paris, France.
  8. 8SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, 75005 Paris, France.
  9. 9Institut d’Hématologie et d’Oncologie Pédiatrique, Centre Léon Bérard, 69008 Lyon, France.
  10. 10Equipe Erable, INRIA Grenoble-Rhône-Alpes, 38330 Montbonnot-Saint Martin, France.
  11. 11Gustave Roussy, Université Paris-Saclay, Drug Development Department (DITEP), 94805 Villejuif, France.
  12. 12INSERM U1015, Gustave Roussy, 94805 Villejuif, France.
  1. Corresponding author. Email: aurelien.marabelle{at}gustaveroussy.fr
  • * These authors contributed equally to this work.

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Oct 201936753771407
Nov 201923971096602
Dec 20191355119105
Jan 2020111710174
Feb 202010049478
Mar 20205105754

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