Research ArticleMetabolism

Controlled-release mitochondrial protonophore (CRMP) reverses dyslipidemia and hepatic steatosis in dysmetabolic nonhuman primates

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Science Translational Medicine  02 Oct 2019:
Vol. 11, Issue 512, eaay0284
DOI: 10.1126/scitranslmed.aay0284

Article Information

vol. 11 no. 512

PubMed: 
Print ISSN: 
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History: 
  • Received for publication May 15, 2019
  • Accepted for publication September 13, 2019
  • .

Author Information

  1. Leigh Goedeke1,
  2. Liang Peng1,
  3. Valle Montalvo-Romeral1,
  4. Gina M. Butrico1,
  5. Sylvie Dufour1,
  6. Xian-Man Zhang1,
  7. Rachel J. Perry1,2,
  8. Gary W. Cline1,
  9. Paul Kievit3,
  10. Keefe Chng4,
  11. Kitt Falk Petersen1 and
  12. Gerald I. Shulman1,2,*
  1. 1Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06510, USA.
  2. 2Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT 06510, USA.
  3. 3Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
  4. 4Crown Bioscience Louisiana Inc., New Iberia, LA 70560, USA.
  1. *Corresponding author. Email: gerald.shulman{at}yale.edu

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