Research ArticleCancer

Antibody-mediated targeting of TNFR2 activates CD8+ T cells in mice and promotes antitumor immunity

See allHide authors and affiliations

Science Translational Medicine  02 Oct 2019:
Vol. 11, Issue 512, eaax0720
DOI: 10.1126/scitranslmed.aax0720

Article Information

vol. 11 no. 512

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication February 19, 2019
  • Resubmitted May 22, 2019
  • Accepted for publication August 16, 2019
  • .

Author Information

  1. Eric M. Tam1,*,,
  2. Ross B. Fulton1,*,
  3. James F. Sampson1,*,
  4. Marco Muda1,
  5. Adam Camblin1,
  6. Jennifer Richards1,
  7. Alexander Koshkaryev1,
  8. Jian Tang1,
  9. Vinodh Kurella1,
  10. Yang Jiao1,
  11. Lihui Xu1,
  12. Kathy Zhang1,
  13. Neeraj Kohli1,
  14. Lia Luus1,
  15. Elizabeth Hutto2,
  16. Sandeep Kumar1,
  17. James Lulo1,
  18. Violette Paragas1,
  19. Christina Wong1,
  20. James Suchy1,
  21. Stephanie Grabow1,
  22. Anne-Sophie Dugast1,
  23. Hong Zhang1,
  24. Fabien Depis1,
  25. Sonia Feau1,
  26. Aniela Jakubowski1,
  27. Wenlian Qiao1,
  28. Galina Craig1,
  29. Maja Razlog1,
  30. James Qiu1,
  31. Yu Zhou3,
  32. James D. Marks3,
  33. Michael Croft4,5,
  34. Daryl C. Drummond1 and
  35. Andreas Raue1,
  1. 1Merrimack Pharmaceuticals, Inc., Cambridge, MA 02139, USA.
  2. 2Histo-Scientific Research Laboratories, Mount Jackson, VA 22842, USA.
  3. 3University of California at San Francisco, San Francisco, CA 94110, USA.
  4. 4La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
  5. 5University of California San Diego, La Jolla, CA 92037, USA.
  1. Corresponding author. Email: ertam604{at}gmail.com (E.M.T.); andreas.raue{at}me.com (A.R.)
  • * These authors contributed equally to this work.

Altmetric

Article usage

Article usage: October 2019 to November 2019

AbstractFullPdf
Oct 2019611017461017
Nov 20191577269