Research ArticleCARDIOMETABOLIC DISEASE

Adipose tissue–derived WNT5A regulates vascular redox signaling in obesity via USP17/RAC1-mediated activation of NADPH oxidases

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Science Translational Medicine  18 Sep 2019:
Vol. 11, Issue 510, eaav5055
DOI: 10.1126/scitranslmed.aav5055

Article Information

vol. 11 no. 510

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History: 
  • Received for publication September 26, 2018
  • Accepted for publication August 9, 2019
  • .

Author Information

  1. Ioannis Akoumianakis1,*,
  2. Fabio Sanna1,*,
  3. Marios Margaritis1,
  4. Ileana Badi1,
  5. Nadia Akawi1,
  6. Laura Herdman1,
  7. Patricia Coutinho1,
  8. Harry Fagan1,
  9. Alexios S. Antonopoulos1,
  10. Evangelos K. Oikonomou1,
  11. Sheena Thomas1,
  12. Amy P. Chiu1,
  13. Surawee Chuaiphichai1,
  14. Christos P. Kotanidis1,
  15. Constantinos Christodoulides2,
  16. Mario Petrou3,
  17. George Krasopoulos3,
  18. Rana Sayeed3,
  19. Lei Lv1,
  20. Ashley Hale1,
  21. Meisam Naeimi Kararoudi1,
  22. Eileen McNeill1,
  23. Gillian Douglas1,
  24. Sarah George4,
  25. Dimitris Tousoulis5,
  26. Keith M. Channon1 and
  27. Charalambos Antoniades1,
  1. 1Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 9DU, UK.
  2. 2Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, OX3 7LE, UK.
  3. 3Department of Cardiothoracic Surgery, Oxford University Hospitals NHS Trust, Oxford, OX3 9DU, UK.
  4. 4Bristol Medical School, University of Bristol, Research Floor Level 7, Bristol Royal Infirmary, Bristol BS2 8HW, UK.
  5. 5Cardiology Department, Athens University Medical School, Athens 115 27, Greece.
  1. Corresponding author. Email: antoniad{at}well.ox.ac.uk
  • * These authors contributed equally to this work.

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