Editors' ChoiceCELL THERAPY

Placing skin cells on the assembly line for cardiac repair

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Science Translational Medicine  04 Sep 2019:
Vol. 11, Issue 508, eaaz0306
DOI: 10.1126/scitranslmed.aaz0306

Abstract

Human skin fibroblasts engineered to enhance β-catenin and Gata4 expression secrete vesicles that repair cardiac and skeletal muscle injuries in mice.

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