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Research ArticleTraumatic Brain Injury
In vivo detection of cerebral tau pathology in long-term survivors of traumatic brain injury
- Nikos Gorgoraptis1,
- Lucia M. Li1,
- Alex Whittington1,2,
- Karl A. Zimmerman1,
- Linda M. Maclean3,
- Claire McLeod3,
- Ewan Ross1,
- Amanda Heslegrave4,5,
- Henrik Zetterberg4,5,6,7,
- Jan Passchier2,
- Paul M. Matthews1,8,
- Roger N. Gunn1,2,
- Tom M. McMillan3 and
- David J. Sharp1,8,9,*
- 1Department of Brain Sciences, Imperial College London, London W12 0NN, UK.
- 2Invicro London, London W12 0NN, UK.
- 3Institute of Health and Wellbeing, University of Glasgow, Glasgow G12 0XH, UK.
- 4UK Dementia Research Institute, University College London, London WC1N 3BG, UK.
- 5Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.
- 6Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal 431 80, Sweden.
- 7Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal 413 45, Sweden.
- 8UK Dementia Research Institute, Imperial College London, London W12 0NN, UK.
- 9Royal British Legion Centre for Blast Injury Studies, Imperial College London, London, UK.
- ↵*Corresponding author. Email: david.sharp{at}imperial.ac.uk
See allHide authors and affiliations
Science Translational Medicine 04 Sep 2019:
Vol. 11, Issue 508, eaaw1993
DOI: 10.1126/scitranslmed.aaw1993
Vol. 11, Issue 508, eaaw1993
DOI: 10.1126/scitranslmed.aaw1993
Nikos Gorgoraptis
Department of Brain Sciences, Imperial College London, London W12 0NN, UK.
Lucia M. Li
Department of Brain Sciences, Imperial College London, London W12 0NN, UK.
Alex Whittington
Department of Brain Sciences, Imperial College London, London W12 0NN, UK.Invicro London, London W12 0NN, UK.
Karl A. Zimmerman
Department of Brain Sciences, Imperial College London, London W12 0NN, UK.
Linda M. Maclean
Institute of Health and Wellbeing, University of Glasgow, Glasgow G12 0XH, UK.
Claire McLeod
Institute of Health and Wellbeing, University of Glasgow, Glasgow G12 0XH, UK.
Ewan Ross
Department of Brain Sciences, Imperial College London, London W12 0NN, UK.
Amanda Heslegrave
UK Dementia Research Institute, University College London, London WC1N 3BG, UK.Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.
Henrik Zetterberg
UK Dementia Research Institute, University College London, London WC1N 3BG, UK.Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal 431 80, Sweden.Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal 413 45, Sweden.
Jan Passchier
Invicro London, London W12 0NN, UK.
Paul M. Matthews
Department of Brain Sciences, Imperial College London, London W12 0NN, UK.UK Dementia Research Institute, Imperial College London, London W12 0NN, UK.
Roger N. Gunn
Department of Brain Sciences, Imperial College London, London W12 0NN, UK.Invicro London, London W12 0NN, UK.
Tom M. McMillan
Institute of Health and Wellbeing, University of Glasgow, Glasgow G12 0XH, UK.
David J. Sharp
Department of Brain Sciences, Imperial College London, London W12 0NN, UK.UK Dementia Research Institute, Imperial College London, London W12 0NN, UK.Royal British Legion Centre for Blast Injury Studies, Imperial College London, London, UK.
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