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Neutrophil extracellular traps, B cells, and type I interferons contribute to immune dysregulation in hidradenitis suppurativa

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Science Translational Medicine  04 Sep 2019:
Vol. 11, Issue 508, eaav5908
DOI: 10.1126/scitranslmed.aav5908

Article Information

vol. 11 no. 508

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  • Received for publication October 10, 2018
  • Resubmitted March 20, 2019
  • Accepted for publication July 26, 2019
  • .

Author Information

  1. Angel S. Byrd1,*,,,
  2. Carmelo Carmona-Rivera2,,,
  3. Liam J. O’Neil2,
  4. Philip M. Carlucci2,
  5. Cecilia Cisar3,4,
  6. Avi Z. Rosenberg5,
  7. Michelle L. Kerns1,
  8. Julie A. Caffrey6,
  9. Stephen M. Milner6,
  10. Justin M. Sacks6,
  11. Oluseyi Aliu6,
  12. Kristen P. Broderick6,
  13. Jonathan S. Reichner7,
  14. Lloyd S. Miller1,
  15. Sewon Kang1,
  16. William H. Robinson3,4,
  17. Ginette A. Okoye1,* and
  18. Mariana J. Kaplan2,
  1. 1Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  2. 2Systemic Autoimmunity Branch, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA.
  3. 3VA Palo Alto Health Care System, Palo Alto, CA, USA.
  4. 4Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, USA.
  5. 5Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  6. 6Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  7. 7Division of Surgical Research, Department of Surgery, Rhode Island Hospital, Providence, RI, USA.
  1. Corresponding author. Email: mariana.kaplan{at} (M.J.K.); carmelo.carmona-rivera{at} (C.C.-R.); angel_byrd{at} (A.S.B.)
  • * Present address: Department of Dermatology, Howard University College of Medicine, Washington, DC, USA.

  • These authors contributed equally and share first authorship.


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