Research ArticleHIV

A vaccine-induced gene expression signature correlates with protection against SIV and HIV in multiple trials

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Science Translational Medicine  28 Aug 2019:
Vol. 11, Issue 507, eaaw4236
DOI: 10.1126/scitranslmed.aaw4236

Article Information

vol. 11 no. 507

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History: 
  • Received for publication December 19, 2018
  • Resubmitted February 25, 2019
  • Accepted for publication July 31, 2019
  • .

Author Information

  1. Philip K. Ehrenberg1,*,
  2. Shida Shangguan1,2,*,
  3. Biju Issac1,2,
  4. Galit Alter3,
  5. Aviva Geretz1,2,
  6. Taisuke Izumi1,2,
  7. Christopher Bryant4,
  8. Michael A. Eller1,2,
  9. Frank Wegmann5,
  10. Richard Apps6,
  11. Matthew Creegan1,2,
  12. Diane L. Bolton1,2,
  13. Rafick P. Sekaly7,
  14. Merlin L. Robb1,2,
  15. Robert A. Gramzinski1,
  16. Maria G. Pau5,
  17. Hanneke Schuitemaker5,
  18. Dan H. Barouch3,8,
  19. Nelson L. Michael1,2 and
  20. Rasmi Thomas1,2,
  1. 1U.S. Military HIV Research Program (MHRP), Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
  2. 2Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD 20817, USA.
  3. 3Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
  4. 4EMMES Corporation, Rockville, MD 20850, USA.
  5. 5Janssen Vaccines and Prevention B.V., 2329 Leiden, Netherlands.
  6. 6Center for Human Immunology, National Institutes of Health, Bethesda, MD 20814, USA.
  7. 7Case Western Reserve University, Cleveland, OH 44106, USA.
  8. 8Center for Virology and Vaccine Research, BIDMC, Harvard Medical School, Boston, MA 02115, USA.
  1. Corresponding author. Email: rthomas{at}hivresearch.org
  • * These authors contributed equally to this work.

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