Research ArticleNanomedicine

Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species

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Science Translational Medicine  21 Aug 2019:
Vol. 11, Issue 506, eaaw7736
DOI: 10.1126/scitranslmed.aaw7736

Article Information

vol. 11 no. 506

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  • Received for publication January 24, 2019
  • Accepted for publication July 9, 2019
  • .

Author Information

  1. Tina Binderup1,2,*,
  2. Raphaël Duivenvoorden1,3,*,
  3. Francois Fay1,4,*,
  4. Mandy M. T. van Leent1,
  5. Joost Malkus1,
  6. Samantha Baxter1,
  7. Seigo Ishino1,
  8. Yiming Zhao1,
  9. Brenda Sanchez-Gaytan1,
  10. Abraham J. P. Teunissen1,
  11. Yohana C. A. Frederico1,
  12. Jun Tang1,5,
  13. Giuseppe Carlucci5,6,
  14. Serge Lyashchenko5,7,
  15. Claudia Calcagno1,
  16. Nicolas Karakatsanis1,
  17. Georgios Soultanidis1,
  18. Max L. Senders1,8,
  19. Philip M. Robson1,
  20. Venkatesh Mani1,
  21. Sarayu Ramachandran1,
  22. Mark E. Lobatto1,9,
  23. Barbara A. Hutten10,
  24. Juan F. Granada11,
  25. Thomas Reiner5,7,
  26. Filip K. Swirski12,
  27. Matthias Nahrendorf12,
  28. Andreas Kjaer2,
  29. Edward A. Fisher13,
  30. Zahi A. Fayad1,,
  31. Carlos Pérez-Medina1,14 and
  32. Willem J. M. Mulder1,8,15,16,
  1. 1Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  2. 2Department of Clinical Physiology, Nuclear Medicine and PET and Cluster for Molecular Imaging, Department of Biomedical Sciences, Rigshospitalet and University of Copenhagen, 2100 Copenhagen, Denmark.
  3. 3Department of Nephrology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 XZ Nijmegen, Netherlands.
  4. 4Institut Galien Paris Sud, Faculté de Pharmacie, CNRS, Univ. Paris-Sud, Université Paris-Saclay, 92290 Châtenay-Malabry, France.
  5. 5Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  6. 6Bernard and Irene Schwarz Center for Biomedical Imaging, New York University, New York, NY 10016, USA.
  7. 7Department of Radiology, Weill Cornell Medical College, New York, NY 10065, USA.
  8. 8Department of Medical Biochemistry, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, Netherlands.
  9. 9Department of Radiology, Spaarne Gasthuis, 2035 RC Haarlem, Netherlands.
  10. 10Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam University Medical Centers, 1105 AZ Amsterdam, Netherlands.
  11. 11CRF Skirball Center for Innovation, Cardiovascular Research Foundation, Orangeburg, NY 10962, USA.
  12. 12Center for Systems Biology and Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
  13. 13Department of Medicine (Cardiology) and Cell Biology, Marc and Ruti Bell Program in Vascular Biology, New York University School of Medicine, New York, NY 10016, USA.
  14. 14Centro Nacional de Investigaciones Cardiovasculares Carlos III, 28029 Madrid, Spain.
  15. 15Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  16. 16Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, 5612 AZ Eindhoven, Netherlands.
  1. Corresponding author. Email: willem.mulder{at} (W.J.M.M.); zahi.fayad{at} (Z.A.F.)
  • * These authors contributed equally to this work.


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