Editors' ChoiceAlzheimer’s Disease

Secreted frizzled-related protein 1 frazzles the brain in Alzheimer’s disease

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Science Translational Medicine  07 Aug 2019:
Vol. 11, Issue 504, eaay7697
DOI: 10.1126/scitranslmed.aay7697

Abstract

Inhibition of ADAM10 α-secretase activity in neurons by secreted frizzled-related protein 1 may contribute to Alzheimer’s disease progression.

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