Research ArticleCancer
Personalized circulating tumor DNA analysis to detect residual disease after neoadjuvant therapy in breast cancer
- View ORCID ProfileBradon R. McDonald1,
- Tania Contente-Cuomo1,
- View ORCID ProfileStephen-John Sammut2,
- Ahuva Odenheimer-Bergman1,
- View ORCID ProfileBrenda Ernst3,
- View ORCID ProfileNieves Perdigones1,
- View ORCID ProfileSuet-Feung Chin2,
- View ORCID ProfileMaria Farooq1,
- Rosa Mejia4,
- Patricia A. Cronin3,
- Karen S. Anderson3,5,
- Heidi E. Kosiorek3,
- Donald W. Northfelt3,
- View ORCID ProfileAnn E. McCullough3,
- View ORCID ProfileBhavika K. Patel3,
- View ORCID ProfileJeffrey N. Weitzel4,
- Thomas P. Slavin4,
- View ORCID ProfileCarlos Caldas2,
- View ORCID ProfileBarbara A. Pockaj3,* and
- View ORCID ProfileMuhammed Murtaza1,3,*
- 1Center for Noninvasive Diagnostics, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.
- 2Department of Oncology and Cancer Research UK Cambridge Institute and Cancer Centre, Li Ka Shing Centre, University of Cambridge, Cambridge CB2 0RE, UK.
- 3Mayo Clinic, Scottsdale, AZ 85259, USA.
- 4City of Hope, Duarte, CA 91010, USA.
- 5Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA.
- ↵*Corresponding author. Email: mmurtaza{at}tgen.org (M.M.); pockaj.barbara{at}mayo.edu (B.A.P.)
See allHide authors and affiliations
Science Translational Medicine 07 Aug 2019:
Vol. 11, Issue 504, eaax7392
DOI: 10.1126/scitranslmed.aax7392
Vol. 11, Issue 504, eaax7392
DOI: 10.1126/scitranslmed.aax7392
Bradon R. McDonald
1Center for Noninvasive Diagnostics, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.
Tania Contente-Cuomo
1Center for Noninvasive Diagnostics, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.
Stephen-John Sammut
2Department of Oncology and Cancer Research UK Cambridge Institute and Cancer Centre, Li Ka Shing Centre, University of Cambridge, Cambridge CB2 0RE, UK.
Ahuva Odenheimer-Bergman
1Center for Noninvasive Diagnostics, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.
Brenda Ernst
3Mayo Clinic, Scottsdale, AZ 85259, USA.
Nieves Perdigones
1Center for Noninvasive Diagnostics, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.
Suet-Feung Chin
2Department of Oncology and Cancer Research UK Cambridge Institute and Cancer Centre, Li Ka Shing Centre, University of Cambridge, Cambridge CB2 0RE, UK.
Maria Farooq
1Center for Noninvasive Diagnostics, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.
Rosa Mejia
4City of Hope, Duarte, CA 91010, USA.
Patricia A. Cronin
3Mayo Clinic, Scottsdale, AZ 85259, USA.
Karen S. Anderson
3Mayo Clinic, Scottsdale, AZ 85259, USA.
5Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA.
Heidi E. Kosiorek
3Mayo Clinic, Scottsdale, AZ 85259, USA.
Donald W. Northfelt
3Mayo Clinic, Scottsdale, AZ 85259, USA.
Ann E. McCullough
3Mayo Clinic, Scottsdale, AZ 85259, USA.
Bhavika K. Patel
3Mayo Clinic, Scottsdale, AZ 85259, USA.
Jeffrey N. Weitzel
4City of Hope, Duarte, CA 91010, USA.
Thomas P. Slavin
4City of Hope, Duarte, CA 91010, USA.
Carlos Caldas
2Department of Oncology and Cancer Research UK Cambridge Institute and Cancer Centre, Li Ka Shing Centre, University of Cambridge, Cambridge CB2 0RE, UK.
Barbara A. Pockaj
3Mayo Clinic, Scottsdale, AZ 85259, USA.
Muhammed Murtaza
1Center for Noninvasive Diagnostics, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.
3Mayo Clinic, Scottsdale, AZ 85259, USA.
