Research ArticleGUT MICROBIOTA

The gut microbiota influences skeletal muscle mass and function in mice

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Science Translational Medicine  24 Jul 2019:
Vol. 11, Issue 502, eaan5662
DOI: 10.1126/scitranslmed.aan5662

Article Information

vol. 11 no. 502

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  • Received for publication May 2, 2017
  • Resubmitted September 30, 2018
  • Accepted for publication February 11, 2019
  • .

Author Information

  1. Shawon Lahiri1,2,*,,
  2. Hyejin Kim3,
  3. Isabel Garcia-Perez4,
  4. Musarrat Maisha Reza1,5,
  5. Katherine A. Martin3,
  6. Parag Kundu3,6,
  7. Laura M. Cox7,
  8. Joel Selkrig3,,
  9. Joram M. Posma4,
  10. Hongbo Zhang8,§,
  11. Parasuraman Padmanabhan3,
  12. Catherine Moret2,
  13. Balázs Gulyás9,10,
  14. Martin J. Blaser11,12,
  15. Johan Auwerx8,
  16. Elaine Holmes4,
  17. Jeremy Nicholson13,
  18. Walter Wahli2,3,14 and
  19. Sven Pettersson1,3,6,
  1. 1Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
  2. 2Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
  3. 3Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
  4. 4Division of Computational and Systems Medicine, Department of Surgery and Cancer, Sir Alexander Fleming Building, Imperial College London, London SW72AZ, UK.
  5. 5School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
  6. 6Singapore Center for Environmental Life Sciences Engineering (SCELSE), Nanyang Technological University, Singapore, Singapore.
  7. 7Ann Romney Center for Neurologic Diseases, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
  8. 8Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  9. 9Department of Neuroscience and Mental Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
  10. 10Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  11. 11Department of Medicine, New York University School of Medicine, New York, NY 10016, USA.
  12. 12Medical Service, VA New York Harbor Healthcare System, New York, NY 10010, USA.
  13. 13Australian National Phenome Center, Murdoch University, WA 6150, Australia.
  14. 14INRA ToxAlim Integrative Toxicology and Metabolism UMR1331, Chemin de Tournefeuille, Toulouse Cedex, France.
  1. Corresponding author. Email: sven.pettersson{at} (S.P.); shawonlahiri{at} (S.L.)
  • * Present address: Swedish Research Council, Stockholm, Sweden.

  • Present address: European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany.

  • § Present address: Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Department of Histology and Embryology of Zhongshan School of Medicine, Sun-Yat Sen University, Guangzhou, China.


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