Research ArticleHIV

Heterogeneous antiretroviral drug distribution and HIV/SHIV detection in the gut of three species

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Science Translational Medicine  03 Jul 2019:
Vol. 11, Issue 499, eaap8758
DOI: 10.1126/scitranslmed.aap8758

Article Information

vol. 11 no. 499

Print ISSN: 
Online ISSN: 
  • Received for publication September 7, 2017
  • Resubmitted February 28, 2018
  • Accepted for publication November 9, 2018
  • .

Author Information

  1. Corbin G. Thompson1,
  2. Elias P. Rosen1,
  3. Heather M. A. Prince2,
  4. Nicole White1,
  5. Craig Sykes1,
  6. Gabriela de la Cruz3,
  7. Michelle Mathews3,
  8. Claire Deleage4,
  9. Jacob D. Estes4,5,
  10. Paige Charlins6,
  11. Leila R. Mulder6,
  12. Martina Kovarova3,
  13. Lourdes Adamson7,
  14. Shifali Arora2,
  15. Evan S. Dellon2,
  16. Anne F. Peery2,
  17. Nicholas J. Shaheen2,
  18. Cynthia Gay2,
  19. David C. Muddiman8,
  20. Ramesh Akkina6,
  21. J. Victor Garcia3,
  22. Paul Luciw7 and
  23. Angela D. M. Kashuba1,*
  1. 1Division of Pharmacotherapy and Experimental Therapeutics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  2. 2School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  3. 3Division of Infectious Diseases, Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  4. 4AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, USA.
  5. 5Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, USA.
  6. 6Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA.
  7. 7Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, CA, USA.
  8. 8W.M. Keck FTMS Laboratory for Human Health Research, Department of Chemistry, North Carolina State University, Raleigh, NC, USA.
  1. *Corresponding author. Email: akashuba{at}


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