Research ArticleDENGUE VIRUS

A T164S mutation in the dengue virus NS1 protein is associated with greater disease severity in mice

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Science Translational Medicine  26 Jun 2019:
Vol. 11, Issue 498, eaat7726
DOI: 10.1126/scitranslmed.aat7726

Article Information

vol. 11 no. 498

PubMed: 
Print ISSN: 
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History: 
  • Received for publication April 3, 2018
  • Resubmitted October 11, 2018
  • Accepted for publication December 3, 2018
  • .

Author Information

  1. Kitti Wing Ki Chan1,2,
  2. Satoru Watanabe1,
  3. Jocelyn Y. Jin1,
  4. Julien Pompon1,3,
  5. Don Teng4,
  6. Sylvie Alonso2,5,
  7. Dhanasekaran Vijaykrishna1,4,
  8. Scott B. Halstead6,
  9. Jan K. Marzinek7,
  10. Peter J. Bond7,
  11. Bo Burla8,
  12. Federico Torta8,
  13. Markus R. Wenk8,
  14. Eng Eong Ooi1,2 and
  15. Subhash G. Vasudevan1,2,*
  1. 1Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.
  2. 2Department of Microbiology and Immunology, 5 Science Drive 2, Singapore 117545, Singapore.
  3. 3MIVEGEC, UMR IRD 224-CNRS5290 Université de Montpellier, Montpellier, France.
  4. 4Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia.
  5. 5Immunology Programme, Life Science Institute, National University of Singapore, Singapore 117456, Singapore.
  6. 6Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, MD 20817, USA.
  7. 7Bioinformatics Institute (A*STAR), 30 Biopolis St., Singapore 138671, Singapore.
  8. 8Singapore Lipidomics Incubator (SLING), Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
  1. *Corresponding author Email: subhash.vasudevan{at}duke-nus.edu.sg

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