Editors' ChoiceGene Therapy

Neutralizing antibodies for AAV vectors: The strange case of AAV5

See allHide authors and affiliations

Science Translational Medicine  19 Jun 2019:
Vol. 11, Issue 497, eaax9567
DOI: 10.1126/scitranslmed.aax9567

Abstract

A clinical trial on hemophilia B demonstrated efficient liver targeting with AAV5 in the presence of neutralizing antibodies.

View Full Text