Editors' ChoiceDown’s Syndrome

A bit too much Olig2 in Down’s syndrome

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Science Translational Medicine  05 Jun 2019:
Vol. 11, Issue 495, eaay1425
DOI: 10.1126/scitranslmed.aay1425

Abstract

Overproduction of the Olig2 gene responsible for cerebral cortex neurotransmission may explain cognitive impairment in Down’s syndrome.

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