Research ArticleTissue Engineering

Recapitulating bone development through engineered mesenchymal condensations and mechanical cues for tissue regeneration

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Science Translational Medicine  05 Jun 2019:
Vol. 11, Issue 495, eaav7756
DOI: 10.1126/scitranslmed.aav7756

Article Information

vol. 11 no. 495

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History: 
  • Received for publication November 9, 2018
  • Accepted for publication May 13, 2019
  • .

Author Information

  1. Anna M. McDermott1,2,3,*,
  2. Samuel Herberg4,*,,
  3. Devon E. Mason1,2,
  4. Joseph M. Collins1,2,5,
  5. Hope B. Pearson2,
  6. James H. Dawahare2,
  7. Rui Tang4,
  8. Amit N. Patwa6,
  9. Mark W. Grinstaff6,
  10. Daniel J. Kelly3,
  11. Eben Alsberg4,7,8,,§ and
  12. Joel D. Boerckel1,2,5,§
  1. 1Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  2. 2Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN 46556, USA.
  3. 3Department of Mechanical Engineering, Trinity Center for Bioengineering, Trinity College Dublin, Dublin D02 PN40, Ireland.
  4. 4Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA.
  5. 5Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.
  6. 6Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
  7. 7Department of Orthopaedic Surgery, Case Western Reserve University, Cleveland, OH 44106, USA.
  8. 8National Center for Regenerative Medicine, Division of General Medical Sciences, Case Western Reserve University, Cleveland, OH 44106, USA.
  1. §Corresponding author. Email: ealsberg{at}uic.edu (E.A.); boerckel{at}pennmedicine.upenn.edu (J.D.B.)
  • * These authors contributed equally to this work.

  • Present address: Departments of Ophthalmology, Cell and Developmental Biology, and Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, NY 13210, USA.

  • Present address: Departments of Bioengineering and Orthopaedics, University of Illinois, Chicago, IL 60607, USA.

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Article usage: June 2019 to December 2019

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Jun 201976050511046
Jul 2019415200126
Aug 201923110668
Sep 201915810167
Oct 20191667054
Nov 20191425644
Dec 2019643619