Research ArticleFragile X Syndrome

Sustained correction of associative learning deficits after brief, early treatment in a rat model of Fragile X Syndrome

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Science Translational Medicine  29 May 2019:
Vol. 11, Issue 494, eaao0498
DOI: 10.1126/scitranslmed.aao0498

Article Information

vol. 11 no. 494

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History: 
  • Received for publication January 29, 2018
  • Resubmitted October 19, 2018
  • Accepted for publication May 9, 2019
  • .

Author Information

  1. Antonis Asiminas1,2,3,*,
  2. Adam D. Jackson1,2,3,4,*,
  3. Susana R. Louros1,2,3,,
  4. Sally M. Till1,2,3,,
  5. Teresa Spano1,2,3,4,
  6. Owen Dando1,2,3,5,
  7. Mark F. Bear6,
  8. Sumantra Chattarji2,3,4,
  9. Giles E. Hardingham1,2,3,5,
  10. Emily K. Osterweil1,2,3,,
  11. David J. A. Wyllie1,2,3,4,,
  12. Emma R. Wood1,2,3,4,§,|| and
  13. Peter C. Kind1,2,3,4,§,||
  1. 1Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh EH8 9XD, UK.
  2. 2Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh EH8 9XD, UK.
  3. 3Patrick Wild Centre, University of Edinburgh, Edinburgh EH8 9XD, UK.
  4. 4Centre for Brain Development and Repair, InStem, Bangalore 560065, India.
  5. 5UK Dementia Research Institute at the Edinburgh Medical School, University of Edinburgh, Edinburgh EH8 9XD, UK.
  6. 6Department of Brain and Cognitive Sciences, Howard Hughes Medical Institute, Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  1. ||Corresponding author. Email: p.kind{at}ed.ac.uk (P.C.K.); emma.wood{at}ed.ac.uk (E.R.W.)
  • * These authors contributed equally to this work.

  • These authors contributed equally to this work.

  • These authors contributed equally to this work.

  • § These authors contributed equally to this work.

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