Research ArticleGene Therapy
Phagocytosis-shielded lentiviral vectors improve liver gene therapy in nonhuman primates
- Michela Milani1,2,*,
- Andrea Annoni1,*,
- Federica Moalli3,
- Tongyao Liu4,
- Daniela Cesana1,
- Andrea Calabria1,
- Sara Bartolaccini1,
- Mauro Biffi1,
- Fabio Russo1,
- Ilaria Visigalli1,
- Andrea Raimondi3,
- Susannah Patarroyo-White4,
- Douglas Drager4,
- Patrizia Cristofori1,5,
- Eduard Ayuso6,
- Eugenio Montini1,
- Robert Peters4,
- Matteo Iannacone3,
- Alessio Cantore1,2,†,‡ and
- Luigi Naldini1,2,†,‡
- 1San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
- 2Vita-Salute San Raffaele University, 20132 Milan, Italy.
- 3IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
- 4Bioverativ, Waltham, MA 02451, USA.
- 5GlaxoSmithKline R&D UK, Ware SG12 0DP, UK.
- 6INSERM UMR1089, University of Nantes, CHU de Nantes, 44093 Nantes, France.
- ↵†Corresponding author. Email: cantore.alessio{at}hsr.it (A. Cantore); naldini.luigi{at}hsr.it (L.N.)
See allHide authors and affiliations
Science Translational Medicine 22 May 2019:
Vol. 11, Issue 493, eaav7325
DOI: 10.1126/scitranslmed.aav7325
