22 May 2019
Vol 11, Issue 493

About The Cover

Cover image expansion

ONLINE COVER Taking Cilia to Heart. This image depicts heart valve tissue from a newborn mouse, with cilia highlighted in green, nuclei in blue, and versican (a component of the extracellular matrix) in gray. By tracking the development of heart valves in mice and analyzing gene associations in human patients, Toomer et al. identified an association between cilia defects and mitral valve prolapse, a common congenital heart condition. [CREDIT: KATELYNN TOOMER AND RUSSELL NORRIS/MEDICAL UNIVERSITY OF SOUTH CAROLINA]