Research ArticleCancer

Cediranib suppresses homology-directed DNA repair through down-regulation of BRCA1/2 and RAD51

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Science Translational Medicine  15 May 2019:
Vol. 11, Issue 492, eaav4508
DOI: 10.1126/scitranslmed.aav4508

Article Information

vol. 11 no. 492

PubMed: 
Print ISSN: 
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History: 
  • Received for publication September 17, 2018
  • Resubmitted January 30, 2019
  • Accepted for publication April 15, 2019

Author Information

  1. Alanna R. Kaplan1,2,
  2. Susan E. Gueble1,2,
  3. Yanfeng Liu1,
  4. Sebastian Oeck1,
  5. Hoon Kim1,
  6. Zhong Yun1 and
  7. Peter M. Glazer1,3,*
  1. 1Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06511, USA.
  2. 2Department of Pathology, Yale University School of Medicine, New Haven, CT 06511, USA.
  3. 3Department of Genetics, Yale University School of Medicine, New Haven, CT 06511, USA.
  1. *Corresponding author. Email: peter.glazer{at}yale.edu

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