Research ArticleEMERGING INFECTIONS

A virus-like particle vaccine prevents equine encephalitis virus infection in nonhuman primates

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Science Translational Medicine  15 May 2019:
Vol. 11, Issue 492, eaav3113
DOI: 10.1126/scitranslmed.aav3113

Article Information

vol. 11 no. 492

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History: 
  • Received for publication September 4, 2018
  • Accepted for publication March 21, 2019
  • .

Author Information

  1. Sung-Youl Ko1,*,
  2. Wataru Akahata1,*,,
  3. Eun Sung Yang1,
  4. Wing-Pui Kong1,
  5. Crystal W. Burke2,
  6. Shelley P. Honnold3,
  7. Donald K. Nichols3,
  8. Yan-Jang S. Huang4,
  9. Gretchen L. Schieber1,,
  10. Kevin Carlton1,
  11. Luis DaSilva5,
  12. Vicki Traina-Dorge6,
  13. Dana L. Vanlandingham4,
  14. Yaroslav Tsybovsky7,
  15. Tyler Stephens7,
  16. Ulrich Baxa7,
  17. Stephen Higgs4,
  18. Chad J. Roy6,
  19. Pamela J. Glass2,
  20. John R. Mascola1,§,
  21. Gary J. Nabel1,§,|| and
  22. Srinivas S. Rao1,§,||
  1. 1Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  2. 2Virology Division, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Frederick, MD 21702, USA.
  3. 3Pathology Division, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Frederick, MD 21702, USA.
  4. 4Biosecurity Research Institute and Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA.
  5. 5Center for Aerobiological Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Frederick, MD 21702, USA.
  6. 6Division of Microbiology, Tulane National Primate Research Center, Covington, LA 70433, USA.
  7. 7Electron Microscopy Laboratory, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute, Frederick, MD 21702, USA.
  1. §Corresponding author. Email: jmascola{at}mail.nih.gov (J.R.M.); gary.nabel{at}sanofi.com (G.J.N.); srinivas.rao{at}sanofi.com (S.S.R.)
  • * These authors contributed equally to this work.

  • Present address: VLP Therapeutics, 19 Firstfield Road, Gaithersburg, MD 20878, USA.

  • Present address: Division of Intramural Research, NIAID, NIH, Bethesda, MD 20892, USA.

  • || Present address: Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA.

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