A randomized placebo-controlled pilot trial shows that intranasal vasopressin improves social deficits in children with autism

Karen J. Parker; Ozge Oztan; Robin A. Libove; Noreen Mohsin; Debra S. Karhson; Raena D. Sumiyoshi; Jacqueline E. Summers; Kyle E. Hinman; Kara S. Motonaga; Jennifer M. Phillips; Dean S. Carson; Lawrence K. Fung; Joseph P. Garner; Antonio Y. Hardan

doi:10.1126/scitranslmed.aau7356

Research ArticleAutism Spectrum Disorder

A randomized placebo-controlled pilot trial shows that intranasal vasopressin improves social deficits in children with autism

Karen J. Parker ¹,*,
Ozge Oztan ¹,
Robin A. Libove¹,
Noreen Mohsin¹,
Debra S. Karhson ¹,
Raena D. Sumiyoshi¹,
Jacqueline E. Summers¹,
Kyle E. Hinman¹,
Kara S. Motonaga²,
Jennifer M. Phillips¹,
Dean S. Carson ¹,
Lawrence K. Fung ¹,
Joseph P. Garner¹,³ and
Antonio Y. Hardan ¹

¹Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.
²Department of Pediatrics, Stanford University, Stanford, CA 94305, USA.
³Department of Comparative Medicine, Stanford University, Stanford, CA 94305, USA.

↵*Corresponding author. Email: kjparker{at}stanford.edu

See allHide authors and affiliations

Science Translational Medicine 08 May 2019:
Vol. 11, Issue 491, eaau7356
DOI: 10.1126/scitranslmed.aau7356

Karen J. Parker

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Karen J. Parker
For correspondence: kjparker@stanford.edu

Ozge Oztan

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Ozge Oztan

Robin A. Libove

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Noreen Mohsin

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Debra S. Karhson

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Debra S. Karhson

Raena D. Sumiyoshi

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Raena D. Sumiyoshi

Jacqueline E. Summers

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Jacqueline E. Summers

Kyle E. Hinman

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Kyle E. Hinman

Kara S. Motonaga

Department of Pediatrics, Stanford University, Stanford, CA 94305, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Kara S. Motonaga

Jennifer M. Phillips

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Jennifer M. Phillips

Dean S. Carson

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Lawrence K. Fung

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Lawrence K. Fung

Joseph P. Garner

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.Department of Comparative Medicine, Stanford University, Stanford, CA 94305, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Joseph P. Garner

Antonio Y. Hardan

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Article
Figures & Data
Info & Metrics
eLetters
PDF

eLetters is an online forum for ongoing peer review. Submission of eLetters are open to all. Please read our Terms of Service before submitting your own eLetter.

Submit a Response to This Article

Compose eLetter

Title

Contents

More information about text formats

Plain text

Plain text
No HTML tags allowed.
Web page addresses and e-mail addresses turn into links automatically.
Lines and paragraphs break automatically.

Author Information

Contributors
First name and middle name First or given name, e.g. 'Peter'. Last Name Your last, or family, name, e.g. 'MacMoody'. Email Your email address, e.g. higgs-boson@gmail.com Role / Occupation Your role and/or occupation, e.g. 'Orthopedic Surgeon'. Affiliation Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.

Statement of Competing Interests

Competing interests?

Yes

Please describe the competing interests

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

What code is in the image? Enter the characters shown in the image.

Vertical Tabs

No eLetters have been published for this article.

View Full Text

A randomized placebo-controlled pilot trial shows that intranasal vasopressin improves social deficits in children with autism

Plain text

Vertical Tabs

Science Translational Medicine

Article Tools