Research ArticleCancer

Metabolic reprogramming toward oxidative phosphorylation identifies a therapeutic target for mantle cell lymphoma

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Science Translational Medicine  08 May 2019:
Vol. 11, Issue 491, eaau1167
DOI: 10.1126/scitranslmed.aau1167

Article Information

vol. 11 no. 491

PubMed: 
Print ISSN: 
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History: 
  • Received for publication May 9, 2018
  • Resubmitted November 2, 2018
  • Accepted for publication March 29, 2019
  • .

Author Information

  1. Liang Zhang1,*,
  2. Yixin Yao1,*,
  3. Shaojun Zhang2,*,
  4. Yang Liu1,*,
  5. Hui Guo1,
  6. Makhdum Ahmed1,
  7. Taylor Bell1,
  8. Hui Zhang1,
  9. Guangchun Han2,
  10. Elizabeth Lorence1,
  11. Maria Badillo1,
  12. Shouhao Zhou3,
  13. Yuting Sun4,
  14. M. Emilia Di Francesco4,
  15. Ningping Feng4,
  16. Randy Haun5,
  17. Renny Lan6,
  18. Samuel G. Mackintosh6,
  19. Xizeng Mao2,
  20. Xingzhi Song2,
  21. Jianhua Zhang2,
  22. Lan V. Pham7,
  23. Philip L. Lorenzi8,
  24. Joseph Marszalek4,
  25. Tim Heffernan4,
  26. Giulio Draetta2,4,
  27. Philip Jones4,
  28. Andrew Futreal2,
  29. Krystle Nomie1,
  30. Linghua Wang2, and
  31. Michael Wang1,9,
  1. 1Department of Lymphoma and Myeloma, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  2. 2Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  3. 3Department of Biostatistics, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  4. 4Institute for Applied Cancer Science and Center for Co-Clinical Trials, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  5. 5Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
  6. 6Department of Biochemistry and Molecular Biology and Proteomics Core Facility, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
  7. 7Department of Hematopathology, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  8. 8Proteomics and Metabolomics Core Facility, Department of Bioinformatics and Computational Biology, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  9. 9Department of Stem Cell Transplantation and Cellular Therapy, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  1. Corresponding author. Email: lwang22{at}mdanderson.org (L.W.); miwang{at}mdanderson.org (M.W.)
  • * These authors contributed equally to this work.

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