Research ArticleGENE EDITING

In utero gene editing for monogenic lung disease

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Science Translational Medicine  17 Apr 2019:
Vol. 11, Issue 488, eaav8375
DOI: 10.1126/scitranslmed.aav8375

Article Information

vol. 11 no. 488

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication October 24, 2018
  • Accepted for publication January 3, 2019
  • .

Author Information

  1. Deepthi Alapati1,2,3,4,5,
  2. William J. Zacharias3,4,5,6,
  3. Heather A. Hartman7,
  4. Avery C. Rossidis7,
  5. John D. Stratigis7,
  6. Nicholas J Ahn7,
  7. Barbara Coons7,
  8. Su Zhou3,5,
  9. Hiaying Li7,
  10. Kshitiz Singh7,
  11. Jeremy Katzen3,4,
  12. Yaniv Tomer3,4,
  13. Alexandra C. Chadwick3,5,
  14. Kiran Musunuru3,5,
  15. Michael F. Beers3,4,
  16. Edward E. Morrisey3,4,5,* and
  17. William H. Peranteau7,*
  1. 1Department of Pediatrics Nemours, Alfred I duPont Hospital for Children, Wilmington, DE 19803, USA.
  2. 2Department of Pediatrics Sidney Kimmel Medical College, Thomas Jefferson University Philadelphia, Philadelphia, PA 19107, USA.
  3. 3Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
  4. 4Penn Center for Pulmonary Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
  5. 5Penn Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania Philadelphia, Philadelphia, PA 19104, USA.
  6. 6Division of Pulmonary Biology Cincinnati Children’s Hospital, Department of Pediatrics University of Cincinnati College of Medicine, Cincinnati, OH 45529, USA.
  7. 7Center for Fetal Research, Division of General, Thoracic, and Fetal Surgery, Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  1. *Corresponding author. Email: emorrise{at}pennmedicine.upenn.edu (E.E.M.); peranteauw{at}email.chop.edu (W.H.P.)

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