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Research ArticleCystic Fibrosis
Filamentous bacteriophages are associated with chronic Pseudomonas lung infections and antibiotic resistance in cystic fibrosis
- View ORCID ProfileElizabeth B. Burgener1,*,
- View ORCID ProfileJohanna M. Sweere2,3,
- View ORCID ProfileMichelle S. Bach2,
- View ORCID ProfilePatrick R. Secor4,
- View ORCID ProfileNaomi Haddock3,
- View ORCID ProfileLaura K. Jennings4,
- View ORCID ProfileRasmus L. Marvig5,
- View ORCID ProfileHelle Krogh Johansen6,7,
- View ORCID ProfileElio Rossi6,
- View ORCID ProfileXiou Cao2,
- Lu Tian8,
- Laurence Nedelec9,
- View ORCID ProfileSøren Molin10,
- View ORCID ProfilePaul L. Bollyky2,3,† and
- Carlos E. Milla1,†
- 1Center for Excellence in Pulmonary Biology, Department of Pediatrics, Stanford University, Stanford, CA 94305, USA.
- 2Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA 94305, USA.
- 3Stanford Immunology, Stanford University, Stanford, CA 94305, USA.
- 4Division of Biological Sciences, University of Montana, Missoula, MT 59812, USA.
- 5Center for Genomic Medicine, Rigshospitalet–Copenhagen University Hospital, Copenhagen, Denmark.
- 6Department of Clinical Microbiology, Rigshospitalet, Copenhagen Ø, Denmark.
- 7Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen N, Denmark.
- 8Biomedical Data Science Administration and Statistics, Stanford University, Stanford, CA 94305, USA.
- 9Primary Care and Population Health, Stanford University, Stanford, CA 94305, USA.
- 10The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
- ↵*Corresponding author. Email: eburgener{at}stanford.edu
↵† Co-senior authors.
See allHide authors and affiliations
Science Translational Medicine 17 Apr 2019:
Vol. 11, Issue 488, eaau9748
DOI: 10.1126/scitranslmed.aau9748
Vol. 11, Issue 488, eaau9748
DOI: 10.1126/scitranslmed.aau9748
Elizabeth B. Burgener
1Center for Excellence in Pulmonary Biology, Department of Pediatrics, Stanford University, Stanford, CA 94305, USA.
Johanna M. Sweere
2Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA 94305, USA.
3Stanford Immunology, Stanford University, Stanford, CA 94305, USA.
Michelle S. Bach
2Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA 94305, USA.
Patrick R. Secor
4Division of Biological Sciences, University of Montana, Missoula, MT 59812, USA.
Naomi Haddock
3Stanford Immunology, Stanford University, Stanford, CA 94305, USA.
Laura K. Jennings
4Division of Biological Sciences, University of Montana, Missoula, MT 59812, USA.
Rasmus L. Marvig
5Center for Genomic Medicine, Rigshospitalet–Copenhagen University Hospital, Copenhagen, Denmark.
Helle Krogh Johansen
6Department of Clinical Microbiology, Rigshospitalet, Copenhagen Ø, Denmark.
7Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen N, Denmark.
Elio Rossi
6Department of Clinical Microbiology, Rigshospitalet, Copenhagen Ø, Denmark.
Xiou Cao
2Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA 94305, USA.
Lu Tian
8Biomedical Data Science Administration and Statistics, Stanford University, Stanford, CA 94305, USA.
Laurence Nedelec
9Primary Care and Population Health, Stanford University, Stanford, CA 94305, USA.
Søren Molin
9Primary Care and Population Health, Stanford University, Stanford, CA 94305, USA.
Paul L. Bollyky
2Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA 94305, USA.
3Stanford Immunology, Stanford University, Stanford, CA 94305, USA.
Carlos E. Milla
1Center for Excellence in Pulmonary Biology, Department of Pediatrics, Stanford University, Stanford, CA 94305, USA.
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