Impact of antibiotic treatment and host innate immune pressure on enterococcal adaptation in the human bloodstream

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Science Translational Medicine  10 Apr 2019:
Vol. 11, Issue 487, eaat8418
DOI: 10.1126/scitranslmed.aat8418

Article Information

vol. 11 no. 487

Print ISSN: 
Online ISSN: 
  • Received for publication April 10, 2018
  • Accepted for publication November 10, 2018

Author Information

  1. Daria Van Tyne1,2,3,
  2. Abigail L. Manson3,
  3. Mark M. Huycke4,
  4. John Karanicolas5,
  5. Ashlee M. Earl3 and
  6. Michael S. Gilmore1,2,3,*
  1. 1Department of Ophthalmology and Department of Microbiology, Harvard Medical School, Boston, MA 02114, USA.
  2. 2Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA.
  3. 3Infectious Disease and Microbiome Program, Broad Institute, Cambridge, MA 02142, USA.
  4. 4Department of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
  5. 5Program in Molecular Therapeutics, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
  1. *Corresponding author. Email: michael_gilmore{at}


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Article usage: April 2019 to June 2019

Apr 201997781701574
May 201911077146
Jun 20192031515