eLetters is an online forum for ongoing peer review. Submission of eLetters are open to all. Please read our Terms of Service before submitting your own eLetter.
Research ArticleINFERTILITY
A pannexin 1 channelopathy causes human oocyte death
- Qing Sang1,*,†,
- Zhihua Zhang1,*,
- Juanzi Shi2,*,
- Xiaoxi Sun3,*,
- Bin Li4,*,
- Zheng Yan4,*,
- Songguo Xue5,
- Ai Ai4,
- Qifeng Lyu4,
- Wei Li6,
- Jilin Zhang6,
- Ling Wu4,
- Xiaoyan Mao4,
- Biaobang Chen1,
- Jian Mu1,
- Qiaoli Li1,
- Jing Du7,
- Qiang Sun6,
- Li Jin1,
- Lin He8,
- Shujia Zhu6,
- Yanping Kuang4,† and
- Lei Wang1,9,†
- 1Zhongshan Hospital, State Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
- 2Reproductive Medicine Center, Shaanxi Maternal and Child Care Service Center, Shaanxi 710069, China.
- 3Shanghai Ji Ai Genetics and IVF Institute, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
- 4Reproductive Medicine Center, Shanghai Ninth Hospital, Shanghai Jiao Tong University, Shanghai 200011, China.
- 5Reproductive Medicine Center, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 2000120, China.
- 6Institute of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
- 7Shanghai Institute of Planned Parenthood Research, Shanghai 200011, China.
- 8Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200030, China.
- 9Shanghai Center for Women and Children’s Health, Shanghai 200062, China.
- ↵†Corresponding author. Email: wangleiwanglei{at}fudan.edu.cn (L.W.); kuangyanp{at}126.com (Y.K.); sangqing{at}fudan.edu.cn (Q.S.)
↵* These authors contributed equally to this work.
See allHide authors and affiliations
Science Translational Medicine 27 Mar 2019:
Vol. 11, Issue 485, eaav8731
DOI: 10.1126/scitranslmed.aav8731
Vol. 11, Issue 485, eaav8731
DOI: 10.1126/scitranslmed.aav8731
Qing Sang
Zhongshan Hospital, State Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Zhihua Zhang
Zhongshan Hospital, State Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Juanzi Shi
Reproductive Medicine Center, Shaanxi Maternal and Child Care Service Center, Shaanxi 710069, China.
Xiaoxi Sun
Shanghai Ji Ai Genetics and IVF Institute, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
Bin Li
Reproductive Medicine Center, Shanghai Ninth Hospital, Shanghai Jiao Tong University, Shanghai 200011, China.
Zheng Yan
Reproductive Medicine Center, Shanghai Ninth Hospital, Shanghai Jiao Tong University, Shanghai 200011, China.
Songguo Xue
Reproductive Medicine Center, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 2000120, China.
Ai Ai
Reproductive Medicine Center, Shanghai Ninth Hospital, Shanghai Jiao Tong University, Shanghai 200011, China.
Qifeng Lyu
Reproductive Medicine Center, Shanghai Ninth Hospital, Shanghai Jiao Tong University, Shanghai 200011, China.
Wei Li
Institute of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
Jilin Zhang
Institute of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
Ling Wu
Reproductive Medicine Center, Shanghai Ninth Hospital, Shanghai Jiao Tong University, Shanghai 200011, China.
Xiaoyan Mao
Reproductive Medicine Center, Shanghai Ninth Hospital, Shanghai Jiao Tong University, Shanghai 200011, China.
Biaobang Chen
Zhongshan Hospital, State Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Jian Mu
Zhongshan Hospital, State Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Qiaoli Li
Zhongshan Hospital, State Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Jing Du
Shanghai Institute of Planned Parenthood Research, Shanghai 200011, China.
Qiang Sun
Institute of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
Li Jin
Zhongshan Hospital, State Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Lin He
Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200030, China.
Shujia Zhu
Institute of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
Yanping Kuang
Reproductive Medicine Center, Shanghai Ninth Hospital, Shanghai Jiao Tong University, Shanghai 200011, China.
Lei Wang
Zhongshan Hospital, State Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.Shanghai Center for Women and Children’s Health, Shanghai 200062, China.
Submit a Response to This Article
No eLetters have been published for this article.