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A pannexin 1 channelopathy causes human oocyte death

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Science Translational Medicine  27 Mar 2019:
Vol. 11, Issue 485, eaav8731
DOI: 10.1126/scitranslmed.aav8731

Article Information

vol. 11 no. 485

PubMed: 
Print ISSN: 
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History: 
  • Received for publication October 28, 2018
  • Resubmitted January 14, 2019
  • Accepted for publication March 6, 2019

Author Information

  1. Qing Sang1,*,,
  2. Zhihua Zhang1,*,
  3. Juanzi Shi2,*,
  4. Xiaoxi Sun3,*,
  5. Bin Li4,*,
  6. Zheng Yan4,*,
  7. Songguo Xue5,
  8. Ai Ai4,
  9. Qifeng Lyu4,
  10. Wei Li6,
  11. Jilin Zhang6,
  12. Ling Wu4,
  13. Xiaoyan Mao4,
  14. Biaobang Chen1,
  15. Jian Mu1,
  16. Qiaoli Li1,
  17. Jing Du7,
  18. Qiang Sun6,
  19. Li Jin1,
  20. Lin He8,
  21. Shujia Zhu6,
  22. Yanping Kuang4, and
  23. Lei Wang1,9,
  1. 1Zhongshan Hospital, State Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
  2. 2Reproductive Medicine Center, Shaanxi Maternal and Child Care Service Center, Shaanxi 710069, China.
  3. 3Shanghai Ji Ai Genetics and IVF Institute, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
  4. 4Reproductive Medicine Center, Shanghai Ninth Hospital, Shanghai Jiao Tong University, Shanghai 200011, China.
  5. 5Reproductive Medicine Center, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 2000120, China.
  6. 6Institute of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
  7. 7Shanghai Institute of Planned Parenthood Research, Shanghai 200011, China.
  8. 8Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200030, China.
  9. 9Shanghai Center for Women and Children’s Health, Shanghai 200062, China.
  1. Corresponding author. Email: wangleiwanglei{at}fudan.edu.cn (L.W.); kuangyanp{at}126.com (Y.K.); sangqing{at}fudan.edu.cn (Q.S.)
  • * These authors contributed equally to this work.

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