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Intrinsic cell-penetrating activity propels Omomyc from proof of concept to viable anti-MYC therapy

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Science Translational Medicine  20 Mar 2019:
Vol. 11, Issue 484, eaar5012
DOI: 10.1126/scitranslmed.aar5012

Article Information

vol. 11 no. 484

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication November 15, 2017
  • Resubmitted August 31, 2018
  • Accepted for publication February 18, 2019
  • .

Author Information

  1. Marie-Eve Beaulieu1,2,
  2. Toni Jauset1,2,
  3. Daniel Massó-Vallés1,2,
  4. Sandra Martínez-Martín2,
  5. Peter Rahl3,
  6. Loïka Maltais4,
  7. Mariano F. Zacarias-Fluck2,
  8. Sílvia Casacuberta-Serra1,2,
  9. Erika Serrano del Pozo2,
  10. Christopher Fiore3,
  11. Laia Foradada1,
  12. Virginia Castillo Cano2,
  13. Meritxell Sánchez-Hervás2,
  14. Matthew Guenther3,
  15. Eduardo Romero Sanz5,
  16. Marta Oteo5,
  17. Cynthia Tremblay4,
  18. Génesis Martín2,
  19. Danny Letourneau4,
  20. Martin Montagne4,
  21. Miguel Ángel Morcillo Alonso5,
  22. Jonathan R. Whitfield2,
  23. Pierre Lavigne4 and
  24. Laura Soucek1,2,6,7,*
  1. 1Peptomyc S.L., Edifici Cellex, Hospital Vall d’Hebron, Barcelona, 08035, Spain.
  2. 2Vall d’Hebron Institute of Oncology (VHIO), Edifici Cellex, Hospital Vall d’Hebron, Barcelona, 08035, Spain.
  3. 3Syros Pharmaceuticals, Cambridge, MA 02139, USA.
  4. 4Département de Biochimie, PROTÉO and Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, Quebec J1H 5N4, Canada.
  5. 5Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), Madrid, 28040, Spain.
  6. 6Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, 08010, Spain.
  7. 7Department of Biochemistry and Molecular Biology, Universitat Autònoma de Barcelona, Bellaterra, 08193 , Spain.
  1. *Corresponding author. Email: lsoucek{at}vhio.net

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Mar 201998061553737
Apr 20191284332319
May 2019703222219
Jun 201946611892
Jul 20194049899
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