Research ArticleColitis

PAI-1 augments mucosal damage in colitis

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Science Translational Medicine  06 Mar 2019:
Vol. 11, Issue 482, eaat0852
DOI: 10.1126/scitranslmed.aat0852

Article Information

vol. 11 no. 482

Print ISSN: 
Online ISSN: 
  • Received for publication January 23, 2018
  • Resubmitted October 10, 2018
  • Accepted for publication February 12, 2019
  • .

Author Information

  1. Gerard E. Kaiko1,2,3,
  2. Feidi Chen1,
  3. Chin-Wen Lai1,
  4. I-Ling Chiang1,
  5. Jacqueline Perrigoue4,
  6. Aleksandar Stojmirović4,
  7. Katherine Li4,
  8. Brian D. Muegge1,
  9. Umang Jain1,
  10. Kelli L. VanDussen1,5,
  11. Bridie J. Goggins2,3,
  12. Simon Keely2,3,
  13. Jessica Weaver2,3,
  14. Paul S. Foster2,3,
  15. Daniel A. Lawrence6,
  16. Ta-Chiang Liu1 and
  17. Thaddeus S. Stappenbeck1,*
  1. 1Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  2. 2School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, University of Newcastle, NSW 2308, Australia.
  3. 3Hunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia
  4. 4Janssen Research & Development LLC, Spring House, PA 19002, USA.
  5. 5Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of Cincinnati College of Medicine and the Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA.
  6. 6Departments of Pathology and Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
  1. *Corresponding author. Email: stappenb{at}


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