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Research ArticleADAPTIVE IMMUNITY
Shaping of infant B cell receptor repertoires by environmental factors and infectious disease
- View ORCID ProfileSandra C. A. Nielsen1,*,
- View ORCID ProfileKrishna M. Roskin1,2,3,*,
- View ORCID ProfileKatherine J. L. Jackson1,4,
- View ORCID ProfileShilpa A. Joshi1,
- Parastu Nejad1,
- Ji-Yeun Lee1,
- View ORCID ProfileLisa E. Wagar5,
- Tho D. Pham1,6,
- View ORCID ProfileRamona A. Hoh1,
- View ORCID ProfileKhoa D. Nguyen1,
- View ORCID ProfileHannah Y. Tsunemoto1,
- Sonal B. Patel1,
- View ORCID ProfileRobert Tibshirani7,8,
- View ORCID ProfileCatherine Ley9,
- View ORCID ProfileMark M. Davis5,10,
- View ORCID ProfileJulie Parsonnet9,11,† and
- View ORCID ProfileScott D. Boyd1,†
- 1Department of Pathology, Stanford University, Stanford, CA 94305, USA.
- 2Department of Pediatrics, University of Cincinnati, Cincinnati, OH 45229, USA.
- 3Division of Biomedical Informatics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA.
- 4Immunology Division, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.
- 5Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA.
- 6Stanford Blood Center, Palo Alto, CA 94304, USA.
- 7Department of Biomedical Data Sciences, Stanford University, Stanford, CA 94305, USA.
- 8Department of Statistics, Stanford University, Stanford, CA 94305, USA.
- 9Department of Medicine, Stanford University, Stanford, CA 94305, USA.
- 10Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
- 11Department of Health Research and Policy, Stanford University, Stanford, CA 94305, USA.
- ↵†Corresponding author. Email: sboyd1{at}stanford.edu (S.D.B.); parsonnt{at}stanford.edu (J.P.)
↵* These authors contributed equally to this work.
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Science Translational Medicine 27 Feb 2019:
Vol. 11, Issue 481, eaat2004
DOI: 10.1126/scitranslmed.aat2004
Vol. 11, Issue 481, eaat2004
DOI: 10.1126/scitranslmed.aat2004
Sandra C. A. Nielsen
1Department of Pathology, Stanford University, Stanford, CA 94305, USA.
Krishna M. Roskin
1Department of Pathology, Stanford University, Stanford, CA 94305, USA.
2Department of Pediatrics, University of Cincinnati, Cincinnati, OH 45229, USA.
3Division of Biomedical Informatics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA.
Katherine J. L. Jackson
1Department of Pathology, Stanford University, Stanford, CA 94305, USA.
4Immunology Division, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.
Shilpa A. Joshi
1Department of Pathology, Stanford University, Stanford, CA 94305, USA.
Parastu Nejad
1Department of Pathology, Stanford University, Stanford, CA 94305, USA.
Ji-Yeun Lee
1Department of Pathology, Stanford University, Stanford, CA 94305, USA.
Lisa E. Wagar
5Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA.
Tho D. Pham
1Department of Pathology, Stanford University, Stanford, CA 94305, USA.
6Stanford Blood Center, Palo Alto, CA 94304, USA.
Ramona A. Hoh
1Department of Pathology, Stanford University, Stanford, CA 94305, USA.
Khoa D. Nguyen
1Department of Pathology, Stanford University, Stanford, CA 94305, USA.
Hannah Y. Tsunemoto
1Department of Pathology, Stanford University, Stanford, CA 94305, USA.
Sonal B. Patel
1Department of Pathology, Stanford University, Stanford, CA 94305, USA.
Robert Tibshirani
7Department of Biomedical Data Sciences, Stanford University, Stanford, CA 94305, USA.
8Department of Statistics, Stanford University, Stanford, CA 94305, USA.
Catherine Ley
9Department of Medicine, Stanford University, Stanford, CA 94305, USA.
Mark M. Davis
5Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA.
10Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
Julie Parsonnet
9Department of Medicine, Stanford University, Stanford, CA 94305, USA.
11Department of Health Research and Policy, Stanford University, Stanford, CA 94305, USA.
Scott D. Boyd
1Department of Pathology, Stanford University, Stanford, CA 94305, USA.
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