Research ArticleTHROMBOSIS

Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models

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Science Translational Medicine  13 Feb 2019:
Vol. 11, Issue 479, eaau5898
DOI: 10.1126/scitranslmed.aau5898

Article Information

vol. 11 no. 479

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication April 17, 2018
  • Resubmitted June 26, 2018
  • Accepted for publication January 19, 2019
  • .

Author Information

  1. Anne-Laure Papa1,2,*,
  2. Amanda Jiang3,
  3. Netanel Korin1,,
  4. Michelle B. Chen4,,
  5. Erin T. Langan5,
  6. Anna Waterhouse1,§,||,
  7. Emma Nash1,
  8. Jildaz Caroff5,
  9. Amanda Graveline1,
  10. Andyna Vernet1,
  11. Akiko Mammoto3,,
  12. Tadanori Mammoto3,#,
  13. Abhishek Jain1,**,
  14. Roger D. Kamm4,6,
  15. Matthew J. Gounis5 and
  16. Donald E. Ingber1,3,7,*
  1. 1Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
  2. 2Department of Biomedical Engineering, The George Washington University, Washington, DC 20052, USA.
  3. 3Vascular Biology Program and Department of Surgery, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
  4. 4Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  5. 5New England Center for Stroke Research, Department of Radiology, University of Massachusetts, Worcester, MA 01655, USA.
  6. 6Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  7. 7Harvard John A. Paulson School of Engineering and Applied Sciences, Cambridge, MA 02138, USA.
  1. *Corresponding author. Email: don.ingber{at}wyss.harvard.edu (D.E.I.); alpapa{at}gwu.edu (A.-L.P.)
  • Present address: Department of Biomedical Engineering, Technion–Israel Institute of Technology, Haifa 32000, Israel.

  • Present address: Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.

  • § Present address: Charles Perkins Centre, Faculty of Medicine and Health, University of Sydney, Sydney, NSW 2006, Australia.

  • || Present address: Heart Research Institute, Newtown, NSW 2042, Australia.

  • Present address: Department of Pediatrics, Medical College of Wisconsin, 8701 W Watertown Plank Road, Milwaukee, WI 53226, USA.

  • # Present address: Department of Radiology, Medical College of Wisconsin, 8701 W Watertown Plank Road, Milwaukee, WI 53226, USA.

  • ** Present address: Department of Biomedical Engineering, Texas A&M College of Engineering, Emerging Technologies Building, 101 Bizzell Street, College Station, TX 77843, USA.

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